George Predoiu - Google Academic
Unde să fie examinat pentru prostatită is a discrepancy in the Gleason score given on the initial biopsy and prostatectomy specimen, respectively, that affects both patients who radical prostatectomy benefit from active surveillance and those who cannot benefit from curative surgical treatment, and for whom therapeutic alternatives must be established.
In this context, our study aimed at analyzing the diagnostic concordance between biopsies and subsequent prostatectomies, in order to establish the accuracy of prostate biopsy in predicting final Gleason score of the prostatectomy specimens.
Inclusion Criteria: - Adult men over 40 years old with prostate cancer qualified for radical prostatectomy - Control group formed from 20 healthy men aged years old without any urological conditions and no lower urinary tract symptoms LUTS. Exclusion Criteria: - Neoadjuvant any time before or adjuvant radiotherapy or brachytherapy within the follow-up period of 12 months. Rezultat Măsuri de rezultate primare 1.
Material and methods: We analyzed 79 cases of PADK, initially diagnosed by prostate biopsy and subsequently treated by radical prostatectomy.
The accuracy degree of the tumoral grading system assigned to the prostate biopsy, compared with the radical prostatectomy, was assessed by calculation of the Cohen's kappa concordance coefficient and calculation of sensitivity, specificity, positive prognostic value and negative prognostic value.
Results: 37 cases In prostate biopsies, 32 cases The lowest agreement rate was observed for Gleason score 5, where no case showed a similar score for biopsy and prostatectomy. Statistical analysis indicated a kappa coefficient of 0.
Source: Acta Medica Transilvanica. The purpose of this study is represented by the clinical evaluation of the effectiveness of open radical retropubic prostatectomy with bilateral ilio-obturator lymph node dissection in patients with prostate cancer. We studied a group of patients who underwent open radical retropubic prostatectomy for prostate cancer in localized stage between January - February The average age of patients was
The agreement on ISUP prognostic grade groups between prostate biopsy and radical prostatectomy indicated a slight increase in kappa coefficient Conclusions: Our results demonstrate an increase in the radical prostatectomy accuracy of prostate biopsy, as a result of the application of prognostic grade group system, which ensure the decrease of overestimating tendency of the old scoring system, ultimately leading to a preliminary characterization of potential lesions in prostatectomy specimens and a more radical prostatectomy treatment stratification of patients.
Author Biographies A. Lyon: International Agency for Research on Cancer, A contemporary prostate cancer grading system: A vali-dated alternative to the Gleason score.
Endoscopic Extraperitoneal Radical Prostatectomy, Laparoscopic and Robot-Assisted Surgery
Eur Urol ; 69 3 : Gleason DF. Classification of prostatic carcinomas. Cancer Chemother Rep ; 50 3 Prediction of prognosis for prostatic adenocarcinoma by combined histo-logical grading and clinical staging. J Urol ; 1 : Histological grading and staging of prostatic carcinoma.
Keynote Presentation: Robotic Radical Prostatectomy: Lessons learned from 14,000 cases
Philadephia: Lea and Feibiger, Histologic grading of prostate cancer: a perspective. Hum Pathol ; 23 3 : Am J Surg Pathol ; 29 9 : J Clin Oncol ; 27 21 : J Urol ; 6 : — Epstein JI.
An update of the Gleason grading system. Helpap B, Egevad L. Modified Gleason grading.
An updated review. Histol Histopathol ; 24 5 : Eur Urol ; 58 3 : Arch Pathol Lab Med ; 4 : The impact of the Interna-tional Society of Urological Pathology Gleason grading consensus on active surveillance for prostate cancer. Cent European J Urol ; 70 4 : Upgrading and upstaging in prostate cancer: From prostate biopsy to radical prostatectomy.
- Screening prostate cancer age
- Tratamentul prostatitei funcționale
- Scientific program – Progress in Uro-Oncology
Mol Clin Oncol ; 2 6 : J Clin Oncol ; 34 18 : Front Med Lausanne ; 4: Prostate cancer grading: a decade after the modified system. Mod Pathol ; 31 S1 : SS Grignon DJ. Prostate cancer reporting and staging: needle biopsy and radical radical prostatectomy specimens. Preoperative prediction of Gleason grade in radical prostatectomy specimens: the influence of different Gleason grades from multiple positive biopsy sites.
RADICAL PROSTATECTOMY IN PROSTATE CANCER TREATMENT.
Mod Pathol ; 18 2 : Evaluation of concordance of Gleason score between prostatectomy and biopsies that show more than two different Gleason scores in positive cores. Urology ; 67 1 : Multiple prostate cancer cores with different Gleason grades submitted in the same specimen container without specific site designation: should each core be assigned an individual Gleason score?
Hum Pathol ; 40 4 : Should intervening benign tissue be included in the meas-urement of discontinuous foci of cancer on prostate needle biopsy?
- Log in to Facebook | Facebook
- Suc de roșii pentru tratamentul prostatitei
- Radical Prostatectomy – Results and Tactical Decisions | Medicine and Pharmacy Reports
Correlation with radical prostatec-tomy findings. Am J Surg Pathol ; 35 9 : Continuous versus radical prostatectomy tumor involvement: A di-lemma in prostate biopsy quantitation. Prostate ; 78 15 : Prognostic value of percent Gleason grade 4 at prostate biopsy in predicting prostatectomy pathology and recurrence.
J Urol ; 2 : A critical evaluation of visual proportion of Gleason 4 and maximum cancer core length quantified by histopathologists. Inter-observer variability of cribriform archi-tecture and percent Gleason pattern 4 in prostate cancer: relation to clinical outcome.
Virchows Arch ; 2 : Gleason pattern 4 with cribriform morphology on biopsy is associated with adverse clinicopathological findings in a prospective radical prostatectomy cohort.
Hepatic and Skin Metastases after Laparoscopic Radical Prostatectomy for Prostate Cancer
Hum Pathol ; 98 4 : Hum Pathol ; 99 5 : King CR. Patterns of prostate cancer biopsy grading: trends and clinical implications. Pentru dureri de rinichi J Cancer ; 90 6 : Diagnostic accuracy of prostate biopsy for detecting cribriform Gleason pattern 4 carcinoma and intraductal carcinoma in paired radical prostatectomy specimens: implications for active surveillance.
Humphrey PA. Prostate Pathology. Concordance between Gleason scores of needle biopsies and radical prostatectomy specimens: A population-based study.
BJU Int ; 12 : Gleason score and laterality concordance between prostate biopsy and prostatectomy specimens. Int Braz J Urol ; 35 5 : Comparing the Gleason prostate biopsy and Gleason prosta-tectomy grading system: the Lahey Clinic Medical Center experience and an international meta-analysis.
Radical prostatectomy Urol ; 54 2 : Biopsy Interpretation of the Prostate.
EBSCOhost | | RADICAL PROSTATECTOMY IN PROSTATE CANCER TREATMENT.
Gleason group concordance between biopsy and radical prostatectomy specimens: A cohort study from Prostate Cancer Outcome Registry -Victoria. Prostate Int ; 4 radical prostatectomy : J Clin Oncol ; 33 S7 : Global Gleason grade groups in prostate cancer: concordance of biopsy and radical prostatectomy grades and predictors of upgrade and downgrade. Histopathology ; 70 7 : Pathol Oncol Res ; 26 4 : World J Urol ; 37 10 :